NEET PG 2024 has undergone few changes. There is increased competition in neet pg and increase in number of students. For good rank, good branches of your choice and colleges there is higher competition. For branches of your choice there is higher competition. With all students’ studying short texts, now the concept has changed. Again standard text books and great concept is gaining momentum. In view of more number of conceptual questions asked which negate the need for cramming and memory. A NEET PG student has responsibility of studying in depth, taking classes seriously.
Examination pattern of NEET PG and FMGE has changed. Pure Concepts are needed for preparing the Examinations thoroughly. Most of the Important and Most often asked Questions on subjects need to be revised. One needs the best courses with best Explanations which are High Yielding and more result oriented. Good matter is a source of constant inspiration.
With students feedback who have got good merit and from Experts the students should consult different standard books. The books need to have a great standard because now references and questions are taken from standard texts. The books recommended by experts are
•BD Chaurasia all volumes
•IB SINGH Embryology
•Keith Moore Embryology
It does not imply that all topics need to be studied from these books. But only major and important topics need to be taken care of from books of Dermatology and Orthopedics or Radiology.
But reading Standard Text Books like Harrisons Medicine and Robbins Pathology is important. One cannot neglect these books.
The Coceptual types of Paragraphs are mentioned below from different subjects asked . Like pathology, surgery, medicine .
Topic 1 : Tissue transglutimanase would be seen to generate antigenic epitopes in alpha gliadin in Celiac disease .
Celiac disease is a common immune mediated disease common with HLA DQ2 and HLA DQ8 Positivity . Here IgA antibodies are also found against reticulin which is found in the submucosal layer of the jejunum. There is Presence of Antigliadin antibodies, Antireticulin antibodies, Anti transglutaminase antibodies and Anti endomysial antibodies.
Tissue transglutimanase would be seen to generate antigenic epitopes in alpha gliadin in Celiac sprue.
Topic 2: C282Y Mutations in HFE gene are detected in patients with which Disease ……………….Hemochromatosis
Hemochromatosis is most often caused by inheritance of a mutant HFE gene, which is tightly linked to the HLA-A locus on chromosome 6p . Homozygous C282Y Mutations in HFE gene are detected in many patients with the Hereditary Form of Disease. It is a common disorder of iron storage, in which an appropriate increase in intestinal iron absorption . It results in deposition of excessive amounts of iron in parenchymal cells with eventual tissue damage and impaired function of organs, especially the liver, pancreas, heart, joints, and pituitary.
Topic 3: Vitamin B12 bound to IF is absorbed by…………….. ileal mucosa.
Vitamin B 12 deficiency is an important cause of Megaloblastosis and develops in the vast majority of cases as a result of impaired vitamin B12 absorption. Dietary vitamin B12 is bound to intrinsic factor (IF) secreted by the stomach and vitamin B12 bound to IF is absorbed by ileal mucosa.
Topic 4: Beta 2-microglobulin is produced by ………………….B cells
It is a Protein produced by B-cells; high concentrations in the blood are indicative of multiple myeloma.
Beta-2-Microglobulin is found in the serum of normal individuals and in the urine in elevated amounts in patients with Wilson disease, cadmium poisoning, and other conditions leading to renal tubular dysfunction .
Topic 5: Raised Arginase 1 Levels are seen in Patients with ……….. which Cancer.
Hepatitis C can lead to development of Hepatocellular Cancer. Raised Arginase 1 Levels are seen in Patients with Hepatocellular Cancer.
Topic 6: Hemangioblastomas are seen in association with …………….Von Hippel-Lindau syndrome
Hemangioblastoma is a vascular tumor of unknown histologic origin that frequently develops in the cerebellum of patients with von Hippel-Lindau syndrome. Renal cell carcinomas are also common in this disease. Von Hippel-Lindau syndrome is caused by autosomal dominant mutations of the VHL gene, a tumor suppressor gene.
Topic 7: Perihilar egg -shell calcifications in a glass worker with Progressive Fibrosis of lungs would indicate……………………..which Respiratory Ailment
Silicosis results from inhalation of organic dust of silica. It is common in Miners, Glass workers and Stone workers. Patients usually have a progressive fibrosis of the lung that leads to increasing dyspnea and cough. Silicosis is associated with superinfection by Mycobacterium tuberculosis. Lymph nodes (hilar nodes) show calcifications . Chest radiographic shows nodules, fibrosis and Perihilar egg -shell calcifications
Topic 8: Tacrolimus I acts on cytosolic protein………………………… FKBP
Tacrolimus is an immunosuppresant inhibits T-cell activation by binding to a cytosolic protein FKBP and associates with calcineurin and inhibits the serine/threonine phosphatase activity of this Ca2+-dependent enzyme, thus inhibiting calcineurin-dependent activation of lymphokine expression, apoptosis, and degranulation.
Topic 9: Drug acting on Ala-D Ala of cell Wall is………………Pencillin
Penicillin’s inhibit bacterial growth by interfering with the bacterial cell
wall synthesis and not Cell Membrane. Penicillin’s work by inhibiting transpeptidase, the enzyme that catalyzes the final crosslinking step in peptidoglycan cell wall formation . Penicillins are structural analogs of D-Ala-D-Ala.
Topic 10: A 44 Year old male has been having abdominal cramps and intractable diarrhea. Echo Demonstrates pulmonary valve stenosis. Most Likely Implicated Substance is ………………5-Hydroxyindoleacetic acid
Carcinoid disease primarily involves the right side (although left side lesions may also occur. Most patients with cardiac lesion develop heart failure. The Predominant valvular lesion due to involvement of pulmonary valve is pulmonic stenosis. There is severe involvement of endocardium by dense fibrous deposits. Main secretary product of tumor cells of Carcinoid syndrome is 5HT (5-hydroxyindoleacetic acid) which is responsible for diarrhea and wheezing.
Students are in fierce competition. But one should not get distracted and should continue with his/ her efforts.
Each and every mark counts and most of the Aspirants of NEET PG aim for good merit and scores so that they get the right placement in best medical colleges and hospitals.
Students take Standard Tests of Practice like NEET Pg and Best Question Banks. To go to Packages which most students take for Neet Pg